I-Retatrutide 5mg 10mg intengo eshibhile

incazelo emfushane:

Igama: Retatrutide

Imininingwane: 5mg/vial*10vials/box 10mg/vial*10vial/box

Inani: 5mg USD170/ibhokisi 10mg USD340/ibhokisi

Ilebhu: Lianfu Bio

I-MOQ: Ibhokisi elingu-1

Thumela i-imeyili kithi

Imininingwane Yomkhiqizo

Isevisi yethu kanye Nenqubomgomo

Inqubo yoku-oda

Igama lomkhiqizo: Retatrutide

Ukucaciswa: 5mg*10vial/kit 10mg*10vials/kit

I-MOQ: 1 kit

Intengo: 5mg USD320/kit 10mg USD600/kit

Indawo Yomsuka: China

I-Retatrutide

I-Retatrutide (LY-3437943) isathuthukiswa ukuze zelaphe uhlobo 2 lwesifo sikashukela, i-obstructive sleep apnea, i-osteoarthritis, ukukhuluphala kanye nesifo sesibindi esinamafutha angenalo utshwala.Ikhandidethi lomuthi lilawulwa ngomzila ongaphansi kwesikhumba kanye ne-intravenous.Umuntu ozokhethwa emuthini wenza ngokukhomba i-glucagon-like peptide 1 (GLP-1), i-insulinotropic polypeptide (GIP) encike ku-glucose, kanye nama-glucagon receptors.Kuyinhlangano entsha yamangqamuzana.

I-Retatrutide isebenza ekwelapheni ukukhuluphala ngokukhomba amahomoni amathathu ahlukene alawula indlala: – I-GIP (i-gastric inhibitory peptide noma i-insulinotropic polypeptide encike ku-glucose) iyi-hormone ye-incretin ekhishwa emathunjini ngemva kokudla.I-Retatrutide ivuselela ama-beta-cell ku-pancreas ukuthi akhiphe i-insulin.Umuthi uyi-peptide ene-amino acid ngokulandelana.Kuyi-agonist yama-hormone receptor kathathu we-GLP-1, GIP, kanye ne-GCGR receptors.Kuye kwaboniswa ukuzuza ukwehliswa kwesisindo esingaphezu kuka-24% kubantu abadala abangenaso isifo sikashukela noma abakhuluphele ngokweqile.

I-Retatrutide ifana ne-Ozempic, Wegovy, ne-Mounjaro ngoba iwumjovo wamahomoni kanye ngeviki oshintsha indlela esidla ngayo, okuholela emizweni yokuqala yokusutha kanye nokuncipha kwesifiso sokudla.

Kodwa ngokungafani ne-Ozempic ne-Wegovy, abalingisa ihomoni eyodwa kuphela elawula indlala (GLP-1), noma i-Mounjaro, elingisa amahomoni amabili (i-GLP-1 ne-GIP),i-retatrutidei-molecule eyodwa elingisa amahomoni amathathu ahlukene alawula indlala: i-GLP-1, i-GIP, ne-glucagon.Leso senzo “sika-G” esiphindwe kabili, njengoba abanye ososayensi basibiza kanjalo emhlanganweni, sibonakala sinethonya elinamandla ekufuneni komuntu ukudla nokwaneliseka ngokudla.

Ocwaningweni olushicilelwe ku-NEJM, iziguli ezinokukhuluphala ezinikezwe isilinganiso esiphezulu samasonto onkei-retatrutide(12 mg) ulahlekelwe isilinganiso samaphawundi angama-58 ezinyangeni eziyi-11.Isisindo sabo sasisehla ngisho nalapho uhlolo luphela, okuphakamisa ukuthi izivivinyo ezinde, ezinkulu ezisazoqedwa zingase zilethe imiphumela emangalisa nakakhulu yokuncipha kwesisindo.Isiguli ngasinye esinethamo eliphezulu kakhulu le-retatrutide silahlekelwe okungenani ngu-5% wesisindo somzimba waso, futhi ingxenye yesine yalabo ababambiqhaza yalahlekelwa ngu-30% noma ngaphezulu wesisindo sazo.

Ocwaningweni olufanayo lwe-retatrutide ezigulini ezinesifo sikashukela soHlobo 2 olwanyatheliswa kuyi-Lancet, iziguli zalahlekelwa cishe u-17% wesisindo somzimba wazo ezinyangeni eziyisishiyagalolunye, nokuyinto emangalisayo, njengoba ngokuvamile kunzima ezigulini ezine-T2D ukulahlekelwa isisindo esifanayo. njengabanye abantu abakhuluphele nokukhuluphala ngokweqile.