Ukwelashwa kwe-TB-500 peptide: ukusetshenziswa, umthamo, nokuphepha

Ixhasiwe: Uma ungumcwaningi ofuna ukufaka i-TB-500 emsebenzini wakho, lo mhlahlandlela uzokunikeza ulwazi lwakamuva mayelana nendlela yokusebenza ye-TB-500, ukusetshenziswa, kanye nemiphumela engemihle.

I-TB-500 inguqulo yokwenziwa ye-peptide thymosin beta-4 eyenzeka ngokwemvelo, i-timbetasin.Ucwaningo nge-TB-500 ngokuvamile lubhekisela kuyo njenge-synthetic thymosin beta-4.

Izifundo zabantu ku-TB-500 ziyashoda, kodwa i-peptide iyisihloko socwaningo olusebenzayo ngenxa yezakhiwo ezivuselelayo ze-thymosin beta-4.

I-Thymosin beta-4 itholakala kuwo wonke amangqamuzana asemzimbeni womuntu ngaphandle kwama-erythrocyte, futhi kucatshangwa ukuthi idlala indima ku-angiogenesis, ukuphulukiswa kwamanxeba, nokwanda kwamangqamuzana, ukwahlukanisa, nokufuduka.

Uma ungumcwaningi ofuna ukufaka i-TB-500 emsebenzini wakho, lo mhlahlandlela uzokunikeza ulwazi lwakamuva mayelana nendlela yokusebenza kwe-TB-500, ukusetshenziswa, kanye nemiphumela engemihle.

Siphinde sihlanganise imininingwane yokuthi idosi futhi iphathwa kanjani i-TB-500 kuzilungiselelo zocwaningo, kanye nokuthi ungayithola kuphi i-99% yobumsulwa be-TB-500 ku-inthanethi.

PS: Oda i-TB-500 ku-inthanethi lapha!

Iyini i-TB-500?

I-TB-500 iwuhlobo lokwenziwa lwe-thymosin beta-4 (TB4), i-peptide yomuntu engapheli eyakhiwe ngama-amino acid angama-43 futhi ingatholakala cishe kuwo wonke amaseli omzimba, ikakhulukazi kuma-platelet namaseli amhlophe egazi [1].I-TB4 yaqala ukuhlukaniswa ngo-1981 ngu-Low no-Goldstein ekukhishweni kwe-bovine thymus gland [2].

Inguqulo yokwenziwa, i-TB-500, ayizange ivunyelwe ukuthi isetshenziswe abantu futhi itholakala kuphela njengekhemikhali yocwaningo.Yaqala ukwenziwa ekuqaleni kwawo-2010 ukuze isetshenziswe ezilwaneni.I-TB-500 isetshenziswe njenge-ejenti ye-doping emjahweni wamahhashi futhi yavalwa ngokulandelana ngokunikeza inzuzo engalungile kulowo mdlalo [3, 4].

I-Thymosin beta-4 kanye nokuphuma kwayo, okuhlanganisa i-TB-500, ngokufanayo ivinjelwe yi-World Anti-Doping Agency (WADA) futhi ngaleyo ndlela inqatshelwe ukusetshenziswa ngabasubathi abaqhudelanayo ngaphansi kweKhodi ye-WADA kanye nezigungu ezilawulayo kazwelonke nezesifunda ezifanayo [5].

I-TB-500 noma kunjalo ingaphansi kocwaningo olusebenzayo ngemiphumela yayo engaba khona ekufudukeni kwamangqamuzana nokulungiswa kwezicubu, ukwakheka kwemithambo yegazi emisha, ukuvuthwa kwamangqamuzana e-stem, ukusinda kwezinhlobo zamaseli ahlukahlukene, kanye nesenzo sokulwa nokuvuvukala [1, 6].

I-TB-500 kanye ne-thymosin beta-4 inokungatholakali kahle kwe-oral bioavailability, futhi ngaleyo ndlela ingalawulwa kuphela ngemijovo ezilungiselelweni zokuhlola.

Nokho, ucezwana olwenzeka ngokwemvelo lwe-thymosin beta-4, olubizwa nge-N-acetyl seryl-aspartyl-lysyl-proline (Ac-SDKP), i-peptide esebenza ngomlomo okucatshangwa ukuthi ine-antifibrotic efanayo, anti-inflammatory, izakhiwo ze-angiogenic, kanye nemiphumela ukufuduka kwamaseli nokusinda [7, 8].

Kuye kwaphenywa njenge-inhibitor ye-hematopoietic stem cell proliferation kanye ne-agent chemoprotective [9, 10].Abacwaningi bangathola ucezu lwe-TB-500 lufakwe kumafomula e-capsule ye-TB-500 ahloselwe ukukhanda nokululama kwezicubu.

I-TB-500 Dosage Calculator neshadi

Kuyaphawuleka ukuthi ngenxa yokuntuleka kocwaningo olushicilelwe nge-TB-500, okwamanje azikho izincomo ezithile zomthamo ngezinjongo zocwaningo.

Ucwaningo olutholakalayo ngokuyinhloko lubandakanya amamodeli ezilwane noma izifundo ezihlolwayo, futhi okutholwe kulezi zifundo ngeke kusetshenziswe ngokuqondile kubantu.

Izifundo zabantu ezilinganiselwe ezenziwe ngomjovo we-thymosin beta-4 zibika umthamo we-TB-500 ohluka kakhulu futhi olawulwa ngesikhathi esiphezulu sezinsuku eziyi-14.Azikho izifundo zomtholampilo ezibandakanya izifundo zokwelashwa kwe-peptide ye-TB-500 isikhathi eside kunamasonto amabili [29, 30].

Kungenjalo, i-thymosin beta-4 nayo isetshenziswe ngempumelelo ekuhlolweni komtholampilo ekugxilweni kuka-0.03% ngaphezu kwezinyanga ezintathu.Ukusetshenziswa kwezihloko kuphinde kwabonisa ukuphepha okuhle nokubekezeleleka [20].

Ngokusekelwe olwazini lwamanje, imijovo ye-TB-500 yokululama yokulimala ingase inikezwe ngokusekelwe kulolu hlelo olulandelayo:

• I-TB-500 Umthamo Wansuku zonke: 2mg, ilawulwa ngaphansi kwesikhumba
• Isikhathi Sokufunda: Izinsuku eziyi-15
• Amanothi: Izimbiza ezintathu ze-TB-500 10mg ziyadingeka ukuze kuqedelwe le nqubo yomthetho.Ukulandela isikhathi samasonto amabili, abacwaningi bangaqhubeka nokunikeza umthamo wansuku zonke wesondlo we-1mg, njengoba kudingeka, ukuze bathole ukululama okuphelele noma okuseduze.

Ukuze uthole ulwazi oluthe xaxa mayelana nomthamo we-TB-500, bheka okuningiliziwe kwethuI-TB-500 Dosage Calculator neshadi.

Ungayithenga kuphi i-TB-500 ku-inthanethi?

NiniUkuthola i-TB-500 ku-inthanethingezinjongo zocwaningo, abathengi be-peptide kufanele bahlole ngokucophelela abathengisi abahlukene mayelana namanani entengo, ukwethembeka, ukubuyekezwa kwamakhasimende, ikhwalithi yomkhiqizo, izindlela zokukhokha ezamukelwayo, kanye nezinga lesevisi yamakhasimende elinikezwayo.

Ngokusekelwe kokuhlangenwe nakho kwethu okubanzi, sisekela ngenhliziyo yonke i-Peptide Sciences njengomthombo onokwethenjelwa webanga locwaningo lwe-TB-500.Irekhodi labo lokuletha imikhiqizo yekhwalithi ngokungaguquki libenza babe ukukhetha okuhle kakhulu kubacwaningi abafuna i-TB-500 ku-inthanethi.

Ukuze uthole i-TB-500 yebanga locwaningo lomjovo, vakashela umhlinzeki wethu ongamkhetha wabacwaningi abahamba phambili emhlabeni wonke.