I-HGH iyi-hormone ekhiqizwa ngokwemvelo ngumzimba.Ihlanganiswa ngempela futhi ifihliwe ngamaseli esikhumba ku-anterior pituitary gland etholakala phansi kobuchopho.I-HGH ivuselela izinqubo eziningi ze-metabolic kumaseli.I-HGH ithinta amaprotheni, amafutha, ama-carbohydrate kanye ne-mineral metabolism.Indima enkulu ye-HGH iwukugqugquzela isibindi ukuthi sikhiphe i-Insulin-like Growth Factor-I (IGF-I).